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KMID : 0358420120550060378
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Korean Journal of Obstetrics and Gynecology
2012 Volume.55 No. 6 p.378 ~ p.383
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25-hydroxyvitamin D levels and body mass index in healthy postmenopausal women
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Jang Sun-Young
Lee Ji-Young
Bae Jae-Man
Lee Chul-Min
Hong Sung-Nam
Kim A-Ri
Kim Heung-Yeol
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Abstract
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Objective: Obesity is associated with alterations in vitamin D (VtD) system. We evaluated the correlation between VtD level and body mass index (BMI), a standard for the evaluation of obesity in postmenopausal women.
Methods: To study the relationship between VtD levels and obesity, we recruited 310 healthy postmenopausal women between January 2005 and March 2011 and analyzed the correlation between BMI and serum 25-hydroxyvitamin D (25-OH-VtD) level. We also analyzed the relationship between serum VtD level and bone health status such as bone mineral density measured by dual-energy X-ray absorptiometry, bone turnover marker, and parathyroid hormone (PTH).
Results: With a cut-off level for VtD deficiency at 30 ng/mL, 98.9% patients showed a VtD deficiency, while 87.8% patients showed a vitamin D deficiency with a 20-ng/mL cut-off level. VtD levels had no significant correlation with age, height, weight, BMI, or bone turnover markers. PTH level and serum 25-OH-VtD level showed a negative correlation. VtD level showed negative correlation with BMI, but statistically not significant.
Conclusion: In this study, most of postmenopausal women (more than 87.8%) had a VtD deficiency, and VtD level showed negative correlation with BMI, but was not statistically significant.
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KEYWORD
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Vitamin D, Body mass index, Obesity, Postmenopause
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